About us
The Mitochondrial Laboratory focuses on evaluation of respiratory activity of isolated mitochondria or mitochondria in situ, i.e. in tissues or cells after mechanical and/or chemical permeabilization. The method of high-resolution respirometry extended by fluorimetric analysis of selected mitochondrial parameters enables simultaneous measurement of oxygen flux, reactive oxygen species production, mitochondrial membrane potential and ATP production in tissue biopsies, homogenates, intact or permeabilized cells (cultured cell lines, platelets, spermatozoa) and isolated mitochondria.
Releated Research themes
- Cardiovascular research
- Experimental intensive care medicine
- Hyperbaric medicine
- Proteomics
- Stem cells
Contact
Biomedical Center
alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí
Members
- Prof. Jitka Kuncová, M.D., Ph.D. – Research Group Leader
- Miroslava Čedíková, M.D.
- Martina Grundmanová, M.D.
- Renata Šťastná