Laboratory of Preclinical studies

About us

The Animal Research Facility is designed to provide all experiments on animals (mice, rats, hamsters, gerbils, guinea-pigs,rabbits, pigs, sheeps and goats) and works as a support of other teams. In addition, there are established animal models allowing to do contract research and scientific cooperation, especially in regenerative medicine and experimental surgery.

The section for small animals allows housing in conventional conditions and in the barrier. This experimental facilities includes fully equipped laboratory allowing to perform all the in vivo experiments, including surgical procedures. The section for the large animals includes clean rooms, in which there are two fully equipped operating theatres and experimental ICU.

We offer:

  • Model of healing of cutaneous wounds in non-diabetic and diabetic rats (both DMI and DMII)
  • Porcine model of healing of normal cutaneous wounds
  • Porcine model of healing of full-thickness cutaneous wounds experimentally infected with bacterial biofilm
  • Porcine model of osteochondral deffect in knee joint
  • Porcine models of fractures of femur
  • In vivo testing of materials for stomatology and maxillofacial surgery
  • In vivo testing of materials for soft tissue augmenations
  • In vivo testing of wide spectrum of implants and prostheses
  • Murine models of experimental infection of Cryptosporidium (both for basic research and evaluation of antiprotozoal drugs)

Releated Research themes


Biomedical Center
alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí


Publications and Patents



Charles University
Faculty of Medicine in Pilsen
Biomedical Center

alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí

T: +420 377 593 810
E: This email address is being protected from spambots. You need JavaScript enabled to view it.


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