Laboratory of Cellular Regenerative Medicine

About us

We explore mechanisms governing regeneration of some organs and tissues. Particularly, we are focused on three fields:

  • The role of stem cells in regeneration generally – we investigate, how the stem cells are stimulated to regeneration behavior, how they are attracted into site of injury, and how the regeneration process occurs.
  • Application potential of stem cells in liver regeneration – we study if and how extrahepatical stem cells (i.e. stem cells out of liver) could support liver regeneration and which mechanisms are utilized – hepatodifferentiation, paracrine effect or cell fusion.
  • The role of dermal fibroblasts in wound healing – we are interested in the ability of dermal fibroblasts to participate in the regulation of healing process, particularly in the persistence of chronic inflammation in the wound site.

Our laboratory is equipped with:

  • essential stuff and machines of cell culture laboratory
  • FACSAriaTM Fusion, BD Bioscience
  • FACSVerseTM Flow cytometer, BD Bioscience
  • Luminex® 200TM, Luminex
  • Inverted fluorescence microscope IX83, Olympus
  • Synergy HT and Synergy H1 Microplate readers, Biotek

We are well trained in cell isolation and culture, immunocytochemistry, flow cytometry, proteins quantification by Luminex ans ELISA methods, cell viability and proliferation analysis. At all projects we also focus on the perfect study design and statistics. To guarantee quality standard, well established methods are performed under standard operating protocols.

Releated Research themes

Contact

Biomedical Center
alej Svobody 1655/76
323 00 Plzen
T: +420 377 593 820
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

Members

  • Lucie Vištejnová, Ph.D., M.Sc. – Research Group Leader
  • Assoc. Prof. Daniel Lysák, Ph.D.
  • Anna Zavaďáková, M.Sc.
  • Azalia Mariel Carranza-Trejo, M.D.
  • Monika Holubová, Ph.D.
  • Martina Dolejšová, M.Sc.
  • Iveta Zímová, B.Sc.

Publications and Patents

News

Contact

Charles Univerzity
Faculty of Medicine in Pilsen
Biomedical Center

alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí

T: +420 377 593 810
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

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