Laboratory of Experimental Neurophysiology

About us

Our goal is to understand mechanisms of memory processing on the level of brain neural networks. We focus on hippocampal circuits and their interactions with neocortical areas. Hippocampal system has been found crucial for declarative memory in humans and certain types of cognitive abilities in animals, namely for orientation and spatial memory. Because we can read the information code in hippocampal pyramidal cells relatively well, this system thus provides a fascinating field offering a direct insight into mechanisms of how brain represents external world and how this information is later recalled.

The lab’s concept is to systematically explore properties of memory processing across networks within hippocampus and connected cortical areas. We mainly record electric activity from populations of place cells in laboratory rats and decode the neural information in high temporal resolution. This enables to study detailed kinetics of memory processing and to relate it with local brain oscillations and behavior.

Releated Research themes

Contact

Biomedical Center
alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí
T: 378 024 830 (831)
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

Members

  • Karel Ježek, M.D., Ph.D. – Research Group Leader
  • František Zitrický, M.D.
  • Lenka Sýkorová, M.Sc.
  • Štěpán Kápl, M.Sc.
  • Zuzana Petránková, Ph.D., M.Sc.
  • Michael Mareš
  • Kristýna Paulová
  • M.C.P. Stephanie Lissette Proskauer-Peña

Publications and Patents

News

Contact

Charles Univerzity
Faculty of Medicine in Pilsen
Biomedical Center

alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí

T: +420 377 593 810
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

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