Publications 2023
Holicek P, Truxova I, Rakova J, Salek C, Hensler M, Kovar M, Reinis M, Mikyskova R, Pasulka J, Vosahlikova S, Remesova H, Valentova I, Lysak D, Holubova M, Kaspar P, Prochazka J, Kasikova L, Spisek R, Galluzzi L, Fucikova J. Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients. Cell Death Dis. 2023 Mar 24;14(3):209. IF 9.696 https://doi.org/10.1038/s41419-023-05728-w
PRAJKA, Lukáš - ČEDÍKOVÁ, Miroslava - PROCHÁZKOVÁ, Anežka - KABÍČKOVÁ, Kateřina - MIKLOVIČOVÁ, Gabriela - GRUNDMANOVÁ, Martina - KUNOVÁ, Magdalena - HUMPLÍK, Jan - BOUDA, Jiří. Subpopulace lymfocytů u pacientek s ovariálním endometriomem a zdravých žen - pilotní studie. Aktuální gynekologie a porodnictví. 2023, 2023(15), 9-15. ISSN 1803-9588.
Peterkova K, Vorel J, Ilgova J, Ostasov P, Fajtova P, Konecny L, Chanova M, Kasny M, Horn M, Dvorak J. Proteases and their inhibitors involved in Schistosoma mansoni egg-host interaction revealed by comparative transcriptomics with Fasciola hepatica eggs. Int J Parasitol. 2023 Feb 6:S0020-7519(23)00032-2. https://doi.org/10.1016/j.ijpara.2022.12.007
Publications 2022
Hejretová Lenka; Weberová Karolína; Čedíková Miroslava; Lysák Daniel; Jindra Pavel; Holubová Monika. Invariantní NKT buňky a jejich využití pro imunomodulaci GvHD – souhrn literatury a preklinická data. Transfuze a hematologie dnes, 28(3), 164-172.
Narayan S, Courcoubetis G, Mason J, Naghdloo A, Kolenčík D, Patterson SD, Kuhn P, Shishido SN. Defining A Liquid Biopsy Profile of Circulating Tumor Cells and Oncosomes in Metastatic Colorectal Cancer for Clinical Utility. Cancers (Basel). 2022 Oct 6;14(19):4891. IF 6.575 https://doi.org/10.3390/cancers14194891
Holý P, Hlaváč V, Ostašov P, Brynychová V, Koževnikovová R, Trnková M, Kopečková K, Měšťáková S, Mrhalová M, Souček P. Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype. Biochimie. 2022 Aug;199:158-169. IF 4.372 https://doi.org/10.1016/j.biochi.2022.04.015
Kolenčík D, Narayan S, Thiele JA, McKinley D, Gerdtsson AS, Welter L, Hošek P, Ostašov P, Vyčítal O, Brůha J, Fiala O, Šorejs O, Liška V, Pitule P, Kuhn P, Shishido SN. Circulating Tumor Cell Kinetics and Morphology from the Liquid Biopsy Predict Disease Progression in Patients with Metastatic Colorectal Cancer Following Resection. Cancers (Basel). 2022 Jan 27;14(3):642. IF 6.575 https://doi.org/10.3390/cancers14030642
Publications 2021
KŘÍŽKOVÁ, Věra - ŠIGUTOVÁ, Pavla - HOLUBOVÁ, Monika - ŠTAMBACHOVÁ, Alena - DOLEJŠOVÁ, Martina - LYSÁK, Daniel - DVOŘÁK, Pavel - VLAS, Tomáš - BUFKA, Jiří - VAŇKOVÁ, Lenka - HRUBÁ, Karolína - NGUYEN, Thu Huyen - MARŠÁLOVÁ, Lucie - BOUŘ, Petr. Blood and Blood Components, Hematopoiesis, Selected Methods Used in Cytology, Histology and Hematology. 1st ed. Prague: Karolinum, 2021. Učební texty Univerzity Karlovy. 89 s. ISBN 978-80-246-4709-8.
Pandey S, Tuma Z, Smrhova T, Cedikova M, Macanova T, Chottova Dvorakova M. Laser Capture Microdissection Coupled Capillary Immunoassay to Study the Expression of PCK-2 on Spatially-Resolved Islets of Rat Langerhans. Pharmaceutics. 2021 Jun 15;13(6):883. IF 6.29 https://doi.org/10.3390/pharmaceutics13060883
Kladnicka I, Cedikova M, Jedlicka J, Kohoutova M, Muller L, Plavinova I, Kripnerova M, Bludovska M, Kuncova J, Mullerova D. Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes. Biomolecules. 2021 Jul 21;11(8):1068. IF 5.88 https://doi.org/10.3390/biom11081068
Lysák D, Hejretová L, Hrabětová M, Jindra P. Should We Stop Collecting the Preoperative Autologous Blood before Bone Marrow Harvest? J Clin Med. 2021 May 14;10(10):2134. IF 4.964 https://doi.org/10.3390/jcm10102134
Machuldova, A., Houdova, L., Kratochvilova, K., Leba, M., Jindra, P., Ostasov, P., Maceckova, D., Klieber, R., Gmucova, H., Sramek, J., & Holubova, M. (2021). Single-Nucleotide Polymorphisms in MICA and MICB Genes Could Play a Role in the Outcome in AML Patients after HSCT. Journal of clinical medicine, 10(20), 4636. IF 4.964 https://doi.org/10.3390/jcm10204636
Lysak, D., Brychtová, M., Leba, M., Čedíková, M., Georgiev, D., Jindra, P., Vlas, T., & Holubova, M. (2021). Long-Term Cryopreservation Does Not Affect Quality of Peripheral Blood Stem Cell Grafts: A Comparative Study of Native, Short-Term and Long-Term Cryopreserved Haematopoietic Stem Cells. Cell transplantation, 30, 9636897211036004. IF 4.139 https://doi.org/10.1177/09636897211036004
Machuldova A, Holubova M, Caputo VS, Cedikova M, Jindra P, Houdova L and Pitule P (2021) Role of Polymorphisms of NKG2D Receptor and Its Ligands in Acute Myeloid Leukemia and Human Stem Cell Transplantation. Front. Immunol. 12:651751. IF 7.97 https://doi.org/10.3389/fimmu.2021.651751
Fiala, O., Ostašov, P., Rozsypalová, A., Hora, M., Šorejs, O., Šustr, J., Bendová, B., Trávníček, I., Filipovský, J., Fínek, J., & Büchler, T. (2021). Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib. Cancer management and research, 13, 4077–4086. IF 3.46 https://doi.org/10.2147/CMAR.S305321
Fiala O, Ostašov P, Rozsypalová A, Hora M, Šorejs O, Šustr J, Bendová B, Trávníček I, Filipovský J, Fínek J, Büchler T. Impact of Concomitant Cardiovascular Medication on Survival of Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib or Pazopanib in the First Line. Target Oncol.2021 Sep;16(5):643-652. IF 4.864 https://doi.org/10.1007/s11523-021-00829-y
Navvabi, N., Kolikova, P., Hosek, P., Zitricky, F., Navvabi, A., Vycital, O., Bruha, J., Palek, R., Rosendorf, J., Liska, V., & Pitule, P. (2021). Altered Expression of MBNL Family of Alternative Splicing Factors in Colorectal Cancer. Cancer genomics & proteomics, 18(3), 295–306. IF 3.48 https://doi.org/10.21873/cgp.20260
Hlaváč, V., Václavíková, R., Brynychová, V., Ostašov P., Koževnikovová, R., Kopečková, K., Vrána, D., Gatěk, J., & Souček, P. (2021). Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response. International journal of molecular sciences, 22(6), 2826. IF 6.208 https://doi.org/10.3390/ijms22062826
Rakova, J., Truxova, I., Holicek, P., Salek, C., Hensler, M., Kasikova, L., Pasulka, J., Holubova, M., Kovar, M., Lysak, D., Kline, J. P., Racil, Z., Galluzzi, L., Spisek, R., & Fucikova, J. (2021). TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients. Oncoimmunology, 10(1), 1889822. IF 7.723 https://doi.org/10.1080/2162402X.2021.1889822
Ulrychová, L., Ostašov, P., Chanová, M., Mareš, M., Horn, M., & Dvořák, J. (2021). Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization. Parasites & vectors, 14(1), 274. IF 4.047 https://doi.org/10.1186/s13071-021-04773-8
Publications 2020
Hejretová L, Čedíková M, Dolejšová M, Vlas T, Jindra P, Lysák D, Holubová M. Comparison of the immunomodulatory effect of single MSC batches versus pooled MSC products. Cell Tissue Bank. 2020 Mar;21(1):119-129. https://doi.org/10.1007/s10561-019-09805-3
Fiala, O., Sorejs, O., Hosek, P., Liska, V., Vycital, O., Bruha, J., Kucera, R., Topolcan, O., Finek, J., Maceckova, D., & Pitule, P. (2020). Association of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With Metastatic Colorectal Cancer. Cancer genomics & proteomics, 17(5), 605–613. https://doi.org/10.21873/cgp.20217
Ostasov P., Robertson, H., Piazza, P., Datta, A., Apperley, J., Houdova, L., Lysak, D., Holubova, M., Tesarova, K., Caputo, V. S., & Barozzi, I. (2020). Evolution of Advanced Chronic Lymphoid Leukemia Unveiled by Single-Cell Transcriptomics: A Case Report. Frontiers in oncology, 10, 584607. https://doi.org/10.3389/fonc.2020.584607
Ostasov, P., Tuma, J., Pitule, P., Moravec, J., Houdek, Z., Vozeh, F., Kralickova, M., Cendelin, J., & Babuska, V. (2020). Sonic Hedgehog and Triiodothyronine Pathway Interact in Mouse Embryonic Neural Stem Cells. International journal of molecular sciences, 21(10), 3672. https://doi.org/10.3390/ijms21103672
Tichanek, F., Salomova, M., Jedlicka, J., Kuncova, J., Pitule P., Macanova, T., Petrankova, Z., Tuma, Z., & Cendelin, J. (2020). Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Scientific reports, 10(1), 5418. https://doi.org/10.1038/s41598-020-62308-0
Dekojová, T., Houdová, L., Fatka, J., Pitule, P., Ostašov, P., Caputo, V. S., Gmucová, H., Lysák, D., Jindra, P., & Holubová, M. (2020). Dynamic Changes of Inhibitory Killer-Immunoglobulin-Like Receptors on NK Cells after Allogeneic Hematopoietic Stem Cell Transplantation: An Initial Study. Journal of clinical medicine, 9(11), 3502. https://doi.org/10.3390/jcm9113502
Kolenčík, D., Shishido, S. N., Pitule, P., Mason, J., Hicks, J., & Kuhn, P. (2020). Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges. Cancers, 12(6), 1376. https://doi.org/10.3390/cancers12061376
Holicek, P., Truxova, I., Kasikova, L., Vosahlikova, S., Salek, C., Rakova, J., Holubova, M., Lysak, D., Cremer, I., Spisek, R., and Fucikova, J. (2020). Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood. Methods in enzymology, 631, 277–287. https://doi.org/10.1016/bs.mie.2019.05.034
Publications 2019
Vycital O, Pitule P, Hosek P, Kriz T, Treska V, Liska V. Expression of Serpin B9 as a Prognostic Factor of Colorectal Cancer. Anticancer Res. 2019 Nov;39(11):6063-6066. https://doi.org/10.21873/anticanres.13813
Fiala O, Ostasov P, Hosek P, Sorejs O, Liska V, Buchler T, Poprach A, Kucera R, Topolcan O, Sustr J, Sedivcova M, Finek J. The Predictive Role of Primary Tumour Sidedness in Metastatic Colorectal Cancer Treated With Targeted Agents. Anticancer Res. 2019 Oct;39(10):5645-5652. https://doi.org/10.21873/anticanres.13761
Truxova I, Kasikova L, Salek C, Hensler M, Lysak D, Holicek P, Bilkova P, Holubova M, Chen X, Mikyskova R, Reinis M, Kovar M, Tomalova B, Kline JP, Galluzzi L, Spisek R, Fucikova J. Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients. Haematologica. 2020 Jul;105(7):1868-1878. https://doi.org/10.3324/haematol.2019.223933
Benjamin M. Tang, Maryam Shojaei, …….., Marek Nalos, Monika Holubova, Tracy Chew, David Booth, Anand Kumar, Anthony McLean & Klaus Schughart. Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection. Nature Communications,10, Article number: 3422 (2019) https://doi.org/10.1038/s41467-019-11249-y
Holubova M, Leba M, Gmucova H, Caputo V, Jindra P and Lysak D. Improving the Clinical application of natural killer cells by modulating signals signal from target cells. Int. J. Mol. Sci. 2019, 20, 3472 https://doi.org/10.3390/ijms20143472
P.Holicek, I.Truxova, L.Kasikova, S.Vosahlikova, C.Salek, J.Rakova, M.Holubova, D.Lysak, I.Cremer, R.Spiseka, J.Fucikova. Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood. Methods in Enzymology. June 2019 https://doi.org/10.1016/bs.mie.2019.05.034
Thiele JA, Pitule P, Hicks J, Kuhn P. Single-cell analysis of circulating tumor cells. Methods Mol Biol. 2019;1908:243-264. https://doi.org/10.1007/978-1-4939-9004-7_17
Altanerova U, Jakubechova J, Benejova K, Priscakova P, Pesta M, Pitule P, Topolcan O, Kausitz J, Zduriencikova M, Repiska V, Altaner C. Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes. Int J Cancer. 2019 Feb 15;144(4):897-908. https://doi.org/10.1002/ijc.31792
Publications 2018
Miklíková M, Jarkovská D, Čedíková M, Švíglerová J, Kuncová J, Nalos L, Kubíková T, Liška V, Holubová M, Lysák D, Králíčková M, Vištejnová L, Štengl M. Beneficial effects of mesenchymal stem cells on adult porcine cardiomyocytes in non-contact co-culture. Physiol Res. 2018 Dec 31;67(Supplementum 4):S619-S631 https://doi.org/10.33549/physiolres.934051
Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J. Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res. 2018 Dec 31;67(Suppl 4):S633-S643 https://doi.org/10.33549/physiolres.934046
Hlavac V, Kovacova M, Elsnerova K, Brynychova V, Kozevnikovova R, Raus K, Kopeckova K, Mestakova S, Vrana D, Gatek J, Ostasov P, Vaclavikova R, Soucek P. Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients. Cancers (Basel). 2018 Dec 12;10(12):511. https://doi.org/10.3390/cancers10120511
Rotolo A, Caputo VS, Holubova M, Baxan N, Dubois O, Chaudhry MS, Xiao X, Goudevenou K, Pitcher DS, Petevi K, Kachramanoglou C, Iles S, Naresh K, Maher J, Karadimitris A. Enhanced anti-lymphoma activity of car19-inkt cells underpinned by dual CD19 and CD1d targeting. Cancer Cell. 2018 Oct 8;34(4):596-610. https://doi.org/10.1016/j.ccell.2018.08.017
Thiele JA, Hosek P, Kralovcova E, Ostasov P, Liska V, Bruha J, Vycital O, Rosendorf J, Opattova A, Horak J, Kralickova M, Vodicka P, Pitule P. lncRNAs in Non-Malignant Tissue Have Prognostic Value in Colorectal Cancer. Int J Mol Sci. 2018 Sep 8;19(9):2672. https://doi.org/10.3390/ijms19092672
Polívka J Jr, Pešta M, Pitule P, Hes O, Holubec L, Polívka J, Kubíková T, Tonar Z. IDH1 mutation is associated with lower expression of VEGF but not microvessel formation in glioblastoma multiforme. Oncotarget. 2018 Feb 20;9(23):16462-16476. https://doi.org/10.18632/oncotarget.24536
Fikar P, Georgiev V, Lissorgues G, Holubova M, Lysak D, Georgiev D. 2DEP cytometry: distributed dielectrophoretic cytometry for live cell dielectric signature measurement on population level. BIOMED MICRODEVICES. 2018 Jan 8;20(1):12 https://doi.org/10.1007/s10544-017-0253-5