Journal club: Histone code-derived selection of highly fertile sperm

by Laura Abril-Parreño, Miriam Štiavnická, Olga García-Álvarez
Laboratory of Reproductive Medicine
Thursday 9rd March, 1:00 p.m. (no longer than 20 min. including discussion)

Histone-protamine exchange is specific phenomenon for spermatogenesis and, therefore, sperm chromatin contains mostly protamines. Surprisingly, there are residual histones in sperm head, including the index of their post-translational modifications called „histone code“. Sperm histones obviously do not mean a lapse of Mother Nature but sofisticated tool of sperm for molecular regulation of fertilization and beginning of the life. Accordingly, the most inovative andrological approaches utilize sperm histone code for advanced sperm selection, with respect to their high fertilization ability.


Dear Colleagues, Everybody is invited to come and participate in this event.

Organizers: J. Kroc, l. Vistejnova and P. Klein

About JC:
The goals of Journal Club are manifold. Primarily, it serves as a forum where every member of our biomedical center can present the latest results from his field and specialization in a way that is accessible to her/his colleagues. The first language of JC’s is English. Additionally, it serves as a place to present results from own research and to train presentations. We would like to stimulate discussion across multiple scientific fields in order to reach wider and deeper insight of contemporary development of science. Researchers from outside of the center are welcomed to participate and/or to present their own topics. Please, do not hesitate to come or to contact us.

Journal Club on G+


Charles University
Faculty of Medicine in Pilsen
Biomedical Center

alej Svobody 1655/76
323 00 Plzeň – Severní Předměstí

T: +420 377 593 810
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